Manning JJ - Search Results

1

Promiscuous G-protein activation by the calcium-sensing receptor.

Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu GB, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grassucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR. Zuo H, et al. Among authors: manning jj. Nature. 2024 May;629(8011):481-488. doi: 10.1038/s41586-024-07331-1. Epub 2024 Apr 17. Nature. 2024. PMID: 38632411

2

A Novel "Activation Switch" Motif Common to All Aminergic Receptors.

Lee KH, Manning JJ, Javitch J, Shi L. Lee KH, et al. Among authors: manning jj. J Chem Inf Model. 2023 Aug 28;63(16):5001-5017. doi: 10.1021/acs.jcim.3c00732. Epub 2023 Aug 4. J Chem Inf Model. 2023. PMID: 37540602 Review.

3

Do Toxic Synthetic Cannabinoid Receptor Agonists Have Signature in Vitro Activity Profiles? A Case Study of AMB-FUBINACA.

Finlay DB, Manning JJ, Ibsen MS, Macdonald CE, Patel M, Javitch JA, Banister SD, Glass M. Finlay DB, et al. Among authors: manning jj. ACS Chem Neurosci. 2019 Oct 16;10(10):4350-4360. doi: 10.1021/acschemneuro.9b00429. Epub 2019 Sep 24. ACS Chem Neurosci. 2019. PMID: 31513380 Free PMC article.

4

Signalling profiles of a structurally diverse panel of synthetic cannabinoid receptor agonists.

Patel M, Manning JJ, Finlay DB, Javitch JA, Banister SD, Grimsey NL, Glass M. Patel M, et al. Among authors: manning jj. Biochem Pharmacol. 2020 May;175:113871. doi: 10.1016/j.bcp.2020.113871. Epub 2020 Feb 21. Biochem Pharmacol. 2020. PMID: 32088263

5

Defining Steric Requirements at CB₁ and CB₂ Cannabinoid Receptors Using Synthetic Cannabinoid Receptor Agonists 5F-AB-PINACA, 5F-ADB-PINACA, PX-1, PX-2, NNL-1, and Their Analogues.

Markham J, Sparkes E, Boyd R, Chen S, Manning JJ, Finlay D, Lai F, McGregor E, Maloney CJ, Gerona RR, Connor M, McGregor IS, Hibbs DE, Glass M, Kevin RC, Banister SD. Markham J, et al. Among authors: manning jj. ACS Chem Neurosci. 2022 Apr 20;13(8):1281-1295. doi: 10.1021/acschemneuro.2c00034. Epub 2022 Apr 11. ACS Chem Neurosci. 2022. PMID: 35404067

6

GPCR kinase subtype requirements for arrestin-2 and -3 translocation to the cannabinoid CB₁ receptor and the consequences on G protein signalling.

Manning JJ, Finlay DB, Glass M. Manning JJ, et al. Biochem Pharmacol. 2024 Jun;224:116190. doi: 10.1016/j.bcp.2024.116190. Epub 2024 Apr 9. Biochem Pharmacol. 2024. PMID: 38604257 Free article.

7

The chemistry and pharmacology of putative synthetic cannabinoid receptor agonist (SCRA) new psychoactive substances (NPS) 5F-PY-PICA, 5F-PY-PINACA, and their analogs.

Banister SD, Kevin RC, Martin L, Adams A, Macdonald C, Manning JJ, Boyd R, Cunningham M, Stevens MY, McGregor IS, Glass M, Connor M, Gerona RR. Banister SD, et al. Among authors: manning jj. Drug Test Anal. 2019 Jul;11(7):976-989. doi: 10.1002/dta.2583. Epub 2019 May 8. Drug Test Anal. 2019. PMID: 30838752

8

Positive allosteric modulation of the cannabinoid CB₁ receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics.

Green HM, Manning JJ, Greig IR, Ross RA, Finlay DB, Glass M. Green HM, et al. Among authors: manning jj. Br J Pharmacol. 2024 Jun 3. doi: 10.1111/bph.16433. Online ahead of print. Br J Pharmacol. 2024. PMID: 38831545

9

Methods for automating the analysis of live-cell single-molecule FRET data.

Meszaros J, Geggier P, Manning JJ, Asher WB, Javitch JA. Meszaros J, et al. Among authors: manning jj. Front Cell Dev Biol. 2023 Aug 15;11:1184077. doi: 10.3389/fcell.2023.1184077. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37655158 Free PMC article.

10

Cannabinoid 1 (CB₁ ) receptor arrestin subtype-selectivity and phosphorylation dependence.

Manning JJ, Rawcliffe G, Finlay DB, Glass M. Manning JJ, et al. Br J Pharmacol. 2023 Feb;180(3):369-382. doi: 10.1111/bph.15973. Epub 2022 Nov 6. Br J Pharmacol. 2023. PMID: 36250246 Free PMC article.

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