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The miR-200 family is increased in dysplastic lesions in ulcerative colitis patients.
Lewis A, Felice C, Kumagai T, Lai C, Singh K, Jeffery RR, Feakins R, Giannoulatou E, Armuzzi A, Jawad N, Lindsay JO, Silver A. Lewis A, et al. Among authors: feakins r. PLoS One. 2017 Mar 13;12(3):e0173664. doi: 10.1371/journal.pone.0173664. eCollection 2017. PLoS One. 2017. PMID: 28288169 Free PMC article.
Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion.
Sengupta N, Yau C, Sakthianandeswaren A, Mouradov D, Gibbs P, Suraweera N, Cazier JB, Polanco-Echeverry G, Ghosh A, Thaha M, Ahmed S, Feakins R, Propper D, Dorudi S, Sieber O, Silver A, Lai C. Sengupta N, et al. Among authors: feakins r. Mol Cancer. 2013 Jan 3;12:1. doi: 10.1186/1476-4598-12-1. Mol Cancer. 2013. PMID: 23286373 Free PMC article.
DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid.
MacFie TS, Poulsom R, Parker A, Warnes G, Boitsova T, Nijhuis A, Suraweera N, Poehlmann A, Szary J, Feakins R, Jeffery R, Harper RW, Jubb AM, Lindsay JO, Silver A. MacFie TS, et al. Among authors: feakins r. Inflamm Bowel Dis. 2014 Mar;20(3):514-24. doi: 10.1097/01.MIB.0000442012.45038.0e. Inflamm Bowel Dis. 2014. PMID: 24492313
MCL-1 is modulated in Crohn's disease fibrosis by miR-29b via IL-6 and IL-8.
Nijhuis A, Curciarello R, Mehta S, Feakins R, Bishop CL, Lindsay JO, Silver A. Nijhuis A, et al. Among authors: feakins r. Cell Tissue Res. 2017 May;368(2):325-335. doi: 10.1007/s00441-017-2576-1. Epub 2017 Feb 11. Cell Tissue Res. 2017. PMID: 28190086 Free PMC article.
129 results